Center of Infection and Immunity of Lille
INSERM U1019 – CNRS UMR9017 – Université de Lille – CHU Lille
Director : Jean Dubuisson
The Center for Infection & Immunity of Lille (CIIL) is composed of 14 research teams. The majority of its researchers are biologists specialized in the study of infectious agents and the immune response. The presence of chemists and biophysicists within the CIIL is an additional asset which offers the potential for technological developments in protein chemical synthesis and mechanobiology.
The CIIL develops research projects on the molecular and cellular mechanisms of infectious and chronic inflammatory diseases with the aim of applying this knowledge to the development of improved diagnostics, vaccines and therapeutics.
To achieve these goals, our center gathers complementary expertise, covering a wide range of disciplines including epidemiology, microbiology, virology, parasitology, molecular and cellular biology, immunology, chemistry and biophysics. The CIIL studies bacterial, viral and parasitic diseases and the immune reaction against these infections as well as related immune dysfunctions of non-infectious diseases such as allergic asthma and chronic obstructive pulmonary disease (COPD).
We also work on opportunistic infections in the context of cystic fibrosis which is the most frequent human genetic disease. The major infectious diseases that we investigate are tuberculosis, pneumococcal pneumonia, whooping cough, plague, hepatitis C and E, influenza, Middle East respiratory syndrome (MERS), malaria, schistosomiasis, toxoplasmosis, cryptosporidiosis and blastocystosis. The CIIL focuses its research activities on three major themes: (1) innovative anti-infective approaches, (2) respiratory diseases and (3) emerging zoonotic infectious diseases.
Group leader : Priscille Brodin
Group leader : Jean Dubuisson
Group leader : Philippe Gosset
Group leader : Jamal Khalife
Group leader : Frank Lafont
Group leader : Oleg Melnyk
Group leader : Nathalie Mielcarek
Group leader : Sylviane Pied
Group leader : Florent Sebbane
Group leader : Jean-Claude Sirard
Group leader : François Trottein
Group leader : Anne Tsicopoulos
Group leader : Eric Viscogliosi
Group leader : Ruben Hartkoorn