Lille Platforms in Biology & Health – PLBS – UMS 2014 – US 41
The BioImaging Center Lille (BICeL) is the academic platform for imaging, histology and cytometry of the University Hospital campus, the Faculty of Science and Technology and the Pasteur Institute of Lille.
BICeL brings together expertise, know-how, and equipment across four platforms: (1) flow cytometry & imaging, (2) histology, (3) biophoton microscopy, and (4) electron microscopy. Research & development in imaging techniques extends from the cellular level to tissues and small rodent and aquatic organisms. Located on the campus of the Institut Pasteur in Lille, the site offers access to cutting-edge instruments such as a scanning electron microscope for (cryo)tomography, a cell sorter, and containment microscopes for high-speed, high-resolution video and intravital imaging. BICeL is part of thePLBS Joint Service Unit - UMS 2014 – US 41.
News
The platforms are certified by the Infrastructure in Biology, Health and Agronomy (GIS IBiSA) and are part of a quality assurance process. BICeL has benefited from funding from the EquipEx Future Investment Program (ImagInEx BioMed), supported by the ERDF, the CPER Longevity program, and the University of Lille. Scientific developments are carried out in particular in super-resolution biophotonic microscopy and correlative microscopy with Frank Lafont's team within the Lille Infection and Immunity CenterThe platforms are open to requests from academic and private laboratories.
Members
Frank LAFONT
Director of Unit U1019 – UMR9017 - CNRS research director
N. ORCID: 0000-0001-8668-2580Marc MONGY
IE IPL, photon microscopy platform, technical manager of image analysis
Sophie SALOMÉ
Technical lead for photon microscopy including intravital microscopy
Elisabeth WERKMEISTER
CNRS Research Engineer, Head of Image Analysis and Super-Resolution Microscopy
N. ORCID: 0000-0002-6253-7503Nicolas BAROIS
IR Inserm, Technical Manager, Flow Cytometry and Imaging Platform
Olivier MOLENDI-COSTE
IR Inserm, technical and scientific manager
Keywords
Team contact
Emmanuel Courtade
IE - University of Lille
Publications
BiolCell. 2019 Mar;111(3):67-77.
Blocking bacterial entry at the adhesion step reveals dynamic recruitment of membrane and cytosolic probes.
Nanoscale 11:10320-10328.
Stiffness tomography of eukaryotic intracellular compartments by atomic force microscopy.
2019 PLoS Pathogen 16:e1008106
Rab11A regulated dense granule transport and secretion during Toxoplasma gondii invasions of host cell and parasite replication.
Cell Rep. 2020 Mar 3;30(9):2934-2947.e6. doi: 10.1016/j.celrep.2020.02.013.
Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production.
Nat Commun. 2020 Mar 20;11(1):1509. doi:10.1038/s41467-020-15140-z.
